Another interesting study is called, Localized mesothelioma of the pleura: benign and malignant variants by N Okike, PE Bernatz and LB Woolner - The Journal of Thoracic and Cardiovascular Surgery, Vol 75, 363-372. Here is an excerpt: Mesothelioma, even of the pleura alone, is a ubiquitous pathological designation. The diffuse variety is associated with an ominous prognosis. The localized mesothelioma generally has been assumed to be benign. A...more
Another interesting study is called, Modified RECIST criteria for assessment of response in malignant pleural Mesothelioma by M. J. Byrne and A. K. Nowak - Ann Oncol (2004) 15 (2): 257-260. Here is an excerpt: Abstract - Background: The growth pattern of malignant pleural mesothelioma makes the use of RECIST (response evaluation criteria in solid tumours) response criteria difficult. We have developed and validated Modified RECIST criteria...more
Another interesting study is called, Mesothelioma: profile of keratin proteins and carcinoembryonic antigen: an immunoperoxidase study of 20 cases and comparison with pulmonary adenocarcinomas. - Am J Pathol. 1982 July; 108(1): 8087 by J. M. Corson and G. S. Pinkus. Here is an excerpt: Abstract - The distribution of keratin proteins and carcinoembryonic antigen (CEA) in 20 diffuse pleural malignant mesotheliomas and 20 adenocarcinomas of the lung was determined with the use of an indirect mmunoperoxidase method. Keratin proteins were identified in all of the mesotheliomas, with strong staining observed in 17 of the cases. Tumor cells of various histologic types (tubular, papillary, solid, and spindle) revealed staining for keratin proteins. A variety of staining patterns were observed, but the homogeneous pattern predominated, in either a diffuse (16 cases) or focal form (4 cases). CEA was usually absent (11 cases), but weak or equivocal staining was also observed (8 cases), and 1 case uniquely exhibited moderate staining for CEA. In contrast, adenocarcinomas of the lung usually stained weakly or negatively (18 cases) for keratin proteins and exhibited a predominantly peripheral...more
Another interesting study is called, Value of the Mesothelium-Associated Antibodies Thrombomodulin, Cytokeratin 5/6, Calretinin, and CD44H in Distinguishing Epithelioid Pleural Mesothelioma from Adenocarcinoma Metastatic to the Pleura by P M Cury M.D., D N Butcher, C Fisher M.D., B Corrin M.D. and A G Nicholson D.M. - Mod Pathol 2000;13(2):107112. ...more
Another interesting study is called, Codeletion of p15 and p16 in primary malignant mesothelioma. By Xio S, Li D, Vijg J, Sugarbaker DJ, Corson JM, Fletcher JA. - Oncogene. 1995 Aug 3;11(3):511-5. Department of Pathology, Children's Hospital, Boston, Massachusetts. Here is an excerpt: Abstract - The p15 and p16 CDK4 inhibitor genes map within the...more
Another interesting study is called, Value of calretinin immunostaining in differentiating epithelial mesothelioma from lung adenocarcinoma. By Ordez NG. The University of Texas M.D. Anderson Cancer Center, Houston 77030 - Mod Pathol. 1998 Oct;11(10):929-33. Here is an excerpt: Abstract - Only recently have immunohistochemical markers been recognized that are commonly expressed in epithelial mesotheliomas but not in adenocarcinomas. Among these, calretinin generated a great deal of interest, but the number of studies evaluating the practical use of calretinin immunostaining in the diagnosis of mesothelioma is limited, and the study results are controversial. To evaluate whether calretinin immunostaining can assist in distinguishing between epithelial pleural mesothelioma and lung adenocarcinoma and other carcinomas metastatic to the pleura, 38 pulmonary adenocarcinomas, 117 nonpulmonary adenocarcinomas, 28 squamous cell carcinomas of the lung, 8 large-cell undifferentiated carcinomas of the lung, and 9 transitional cell carcinomas metastatic to the lung were studied. Reactivity was observed in all of the 38 mesotheliomas, whereas only 3 of the 38 pulmonary adenocarcinomas and 11...more
Another interesting study is called, Neoadjuvant Chemotherapy Followed by Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma by Walter Weder, Peter Kestenholz, Christian Taverna, Stefan Bodis, Didier Lardinois, Monika Jerman, Rolf A. Stahel...more
An abdominal hernia occurs when either fatty tissue or an organ in the abdomen protrudes through a weak point or tear in the muscles or tissues around it. The protrusion can be labeled either as reducible, which means it can be pushed...more
American Cancer Treatment Organization is created in order to help people stay well or treat a persons problem. In majority of all cases people find themselves left alone and neglected by other individuals and the society as well. This is the main...more
Mobile phone deals are gaining popularity amongst the mobile lovers. These mobile phone deals have made it easier for the customer to get latest multifunctional handsets at pocket friendly rates. Previously it was a big problem for the...more
The effects of a migraine can be so severe, that some persons will do just about anything to get some relief. This relief can be in the form of medication or alternative treatments.Migraines have been attributed in part, to changes in the body...more
The severity of a migraine headache can sometimes cause so much pain that some people will go to great lengths just to get some relief. Migraines can be treated by the use of prescription medication which can be either abortive or preventive, non...more