One study is called, Immunohistochemical reactivity in mesothelioma and adenocarcinoma: A stepwise logistic regression analysis by Annika Dejmek, Anders Hjerpe - 1994 Acta Pathologica, Microbiologica et Immunologica Scandinavica APMIS Volume 102, Issue 1-6, pages 255264, January 1994. Here is an excerpt: Histological sections from 103 malignant mesotheliomas and 43 adenocarcinoma metastases in pleural biopsies were investigated for reactivity...more
One interesting study is called, Characterization of the IGF System and Analysis of the Possible Molecular Mechanisms Leading to IGF-II Overexpression in a Mesothelioma" by D. Hodzic, L. Delacroix, Ph. Willemsen, K. Bensbaho, J. Collette, R. Broux, P. Lefbvre, J. J. Legros, M. Grooteclaes, R. Winkler - Horm Metab Res 1997; 29(11): 549-555. Here is an excerpt: The expression of members of the IGF system in a mesothelioma from a patient suffering...more
One interesting study is called, Impact of lymph node metastasis on outcome after extrapleural pneumonectomy for malignant pleural Mesothelioma by Marc de Perrot, MD, Karl Uy, MD, Masaki Anraku, MD, Ming S. Tsao, MD, Gail Darling, MD, Thomas K. Waddell, MD, Andrew F. Pierre, MD, Andrea Bezjak, MD, Shaf Keshavjee, MD, Michael R. Johnston, MD - Division of Thoracic Surgery, Toronto General Hospital, University of Toronto, Canada - General Thoracic Surgery J Thorac Cardiovasc Surg 2007;133:111-116. Here is an excerpt: OBJECTIVES: Extrapleural pneumonectomy is a therapeutic option for selected patients with malignant pleural mesothelioma. The impact of lymph node metastasis on the site of recurrence and the role of mediastinoscopy in the selection of patients for extrapleural pneumonectomy, however, remain unclear. METHODS: We reviewed 50 consecutive patients undergoing extrapleural pneumonectomy for malignant pleural mesothelioma in our institution between January 1993 and March 2005. RESULTS: The median survival was 11 months, with a 3-year survival of 24%. Survival was significantly worse for patients with N2 disease than for those with no lymph node metastasis (median survival 10...more
One interesting study is called, Absence of SV40 large T-antigen expression in human mesothelioma cell lines. By Pilatte Y, Vivo C, Renier A, Kheuang L, Greffard A, Jaurand MC - Am J Respir Cell Mol Biol. 2000 Dec;23 (6):788-93. - INSERM, Crteil, France. Here is an excerpt: Abstract - Simian virus (SV) 40 and SV40-like DNA sequences have recently...more
One interesting study is called, The histopathological diagnosis of malignant mesothelioma v. pulmonary adenocarcinoma: reproducibility of the histopathological diagnosis by B.G. Skov1,3,A.F. Lauritzen, F. Hirsch, H.W. Nielsen Histopathology - Volume 24, Issue 6, pages 553557, June 1994. Here is an excerpt: In a randomized design we examined the...more
One interesting study is called, Adenovirus-mediated wild-type p53 overexpression reverts tumourigenicity of human mesothelioma cells. By Giuliano M, Catalano A, Strizzi L, Vianale G, Capogrossi M, Procopio A. Int J Mol Med. 2000 Jun;5(6):591-6. Department of Oncology and Neuroscience, Clinical Pathology Section, Gabriele D'Annunzio University, 66013 Chieti, Italy. Here is an excerpt: Abstract - Pleural malignant mesothelioma (MM) shows poor survival, regardless of tumour stage at diagnosis. MM is unresponsive to present treatment regimens and new protocols are desperately needed. The localised nature, the potential accessibility, and the relative lack of distant metastases make MM a particularly attractive candidate for somatic gene therapy. A common target for cancer gene therapy is the tumour suppressor protein p53. p53 does not seem to be mutated or deleted in MM, but it can be inactivated by binding to other proteins, like mdm2 and SV40 large T antigen. We tested the effects of a replication-deficient adenoviral vector carrying wild-type p53 cDNA in human MM cells. Our results show that >95% of MM cells were efficiently infected with 25 multiplicity of infection (MOI) of...more
Orthotics: The Best Treatment Solution for Foot Disorders Nowadays lots of people complain about distinct kinds of pain due to the hectic daily routines that we have. With proper treatment, the impact that foot pain has on our day to day lives...more
I mentioned in the first video that I have been using Respen-A therapy for just about one year now in my practice. I am recording this particular video in October of 2010 and I plan on continuing to use Respen-A because I have found that it is quite...more
Vitiligo reasons and treatment method Vitiligo is actually a distinct type of leukodermal skin ailment. One among one hundred is noticed to be experiencing this skin ailment. De-pigmentation is the dominant attribute of Vitiligo. Individuals...more
If you are a sufferer of anxiety you will find there are many ways to treat it. Your best bet is to understand what type of anxiety you are dealing with and use the appropriate treatment for it. Whichever treatment you use you will have to monitor it...more
Toenail Treatments Are ImportantIf you have ever had a toenail that was infected by fungus then you know that sometimes it can seem like an impossible ailment to treat! Fungal infections are found underneath the toenail and because of that, they are...more
The Search for a Toenail Fungus CureMore than eleven percent of the inhabitants of North America suffer from a fungal infection of the toenail. Some parts of the world have an even higher infection rate. Each infected person is desperately...more