Another interesting study is called, Genetic alteration of the -catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3 p 21.3 homozygous deletion Oncogene 2001, vol. 20, no31, pp. 4249-4257 by Shigemitsu Kikuo; Sekido Yoshitaka ; Usami Noriyasu; Mori Shoichi; Sato Mitsuo; Horio Yoshitsugu; Hasegawa Yoshinori; Bader Scott A.; Gazdar Adi F. ; Minna John D.; Hida Toyoaki; Yoshioka Hiromu; Imaizumi...more
An interesting study is called, Dickkopf-1 antagonizes Wnt signaling independent of -catenin in human Mesothelioma - Biochemical and Biophysical Research Communications - Volume 323, Issue 4, 29 October 2004, Pages 1246-1250 by Amie Y. Lee, Biao He, Liang You, Zhidong Xu, Julien Mazieres, Noemi Reguart, Iwao Mikami, Sonny Batra and David M. Jablons Here is an excerpt: Abstract - Dickkopf-1 (Dkk-1) is a secreted protein that acts as a potent...more
Another interesting study is called, Lymph Node Metastasis: as the Initial Manifestation of: Malignant Mesothelioma: Report of Six Cases by Sussman, Jeffrey M.D.; Rosai, Juan M.D. Here is an excerpt: Abstract - We present six cases in which lymphadenopathy was the initial manifestation of malignant mesothelioma. In five cases, the primary tumor was located in the peritoneum; it was located in the pleura in the sixth. The involved lymph nodes were cervical in four cases, mediastinal in one, and inguinal in one. The morphologic, immunohistochemical, and ultrastructural features were typical of malignant epithelial mesothelioma. A review of the literature disclosed only one previously documented example of this phenomenon. When confronted with a lymph node involved by metastatic tumor, pathologists should be aware that malignant mesothelioma can present initially in the form of lymphadenopathy and include this possibility in the differential diagnosis.Another interesting study is called, Induction Chemotherapy, Extrapleural Pneumonectomy, and Postoperative High-Dose Radiotherapy for Locally Advanced Malignant Pleural Mesothelioma: A Phase II Trial by Flores, Raja M. MD; Krug, Lee M....more
An interesting study is called, Early Response Evaluation in Malignant Pleural Mesothelioma by Positron Emission Tomography With [18F] Fluorodeoxyglucose by Giovanni L. Ceresoli, Arturo Chiti, Paolo A. Zucali, Marcello Rodari, Romano F. Lutman, Silvia Salamina, Matteo Incarbone, Marco Alloisio, Armando Santoro - Journal of Clinical Oncology, Vol...more
Another interesting study is called, The Human Type 2 Iodothyronine Deiodinase Is a Selenoprotein Highly Expressed in a Mesothelioma Cell Line by Cyntia Curcio, Munira M. A. Baqui, Domenico Salvatore, Bertrand H. Rihn, Steve Mohr, John W. Harney, P. Reed Larsen and Antonio C. Bianco - August 10, 2001 The Journal of Biological Chemistry, 276,...more
Another interesting study is called, Value of thrombomodulin immunostaining in the diagnosis of Mesothelioma by N.G. ORDEZ Histopathology Volume 31, Issue 1, pages 2530, July 1997. Here is an excerpt: Aims: Even with the benefit of immunohistochemistry and electron microscopy, the differential diagnosis between epithelial mesothelioma and pulmonary adenocarcinoma is often difficult. In most instances, the diagnosis of mesothelioma must be reached by the use of immunohistochemical markers that react with adenocarcinomas, but not with mesotheliomas. The purpose of this study is to determine the value of thrombo-modulin (TM) as a positive marker for mesothelioma when distinguishing epithelial pleural mesothelioma from pulmonary adenocarcinoma. Methods and results: TM was expressed in 28 (80%) of 35 epithelial pleural mesotheliomas, but only five (10.9%) of 46 pulmonary adenocarcinomas had appreciable reactivity for this marker. Conclusion: It is concluded that TM can be useful in separating pulmonary adenocarcinoma from epithelial mesothelioma, but it should be used only in conjunction with other immunohistochemical markers that are currently employed in distinguishing between these...more
Have you tried looking in the mirror only to see your shining face? Oily skin is a common problem worldwide. It is because of too much oil production by the sebaceous glands. The oil produced by these glands are necessary to keep your skin healthy....more
Promotional products are oftentimes put to use as marketing tools by most products. But did you know that they can also be used as announcing instruments for charitable functions? Yes! These objects can be maximized as bequests for information drives...more
Your doctor is able to prescribe many treatments for the common complaint of piles, and there are also many that you are able to buy over-the-counter at your local pharmacy, but all these medications have one thing in common. They all treat the...more
Advancements in medical science have led to the development of a range of surgeries to cure vision defects. Laser vision correction methods are the most popular among the contemporary eye surgeries. These methods utilize a special kind of laser...more
Does Dynamiclear really work? Or it is just a Dynamiclear scam? Can it really clear all your Herpes away? Worrying about your Herpes is just as hard as thinking about how to treat it. There are many products in the market nowadays that are claiming...more
Discomfort can be eliminated by Cosmetic Surgery pharmaceuticals given by your cosmetic surgeon. The pain drugs will allow the recovery period to proceed even more smoothly. Going through diminished pain being able to move around is likely to be...more