Per Capita Asbestos Consumption Rate and Mesothelioma Incidence
Who can argue with the facts, exposure to hazardous asbestos can be fatal. Serious doctors have reached a consensus thanks in large part to the myriad of studies researching Mesothelioma and its causes. One interesting study is called, "Ecological Relationship between Mesothelioma Incidence/Mortality and Asbestos Consumption in Ten Western Countries and Japan" by Ken TAKAHASHI, et al. Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health Here is an excerpt: "The objective of the present study was to evaluate the ecological relationship between mesothelioma incidence/mortality and per capita asbestos consumption in ten Western countries and Japan. The two national indices used to assess the geographical correlation were the most recent incidence/mortality rate of mesothelioma for the population over 15 years of age, and the per capita asbestos consumption rate of approximately 10-25 years ago for the population of all ages at that time. Among the ten Western countries, a clear linear relationship was shown between the mesothelioma incidence/mortality rate and the preceding per capita asbestos consumption rate with the Spearman correlation coefficient at 0.70 (p=0.03), and R2-value at 66%. However, the data-point for Japan was situated apart from the linear relationship due to the lower mesothelioma mortality rate, and when combined with other Western countries, the significant relationship diminished. It is possible that the asbestos consumption curve for Japan in past years lagged behind that for the Western countries and the cumulative exposure effect has not yet reached the level that can be expected from other Western countries." (J Occup Health 1999; 41: 8-11)
Another interesting study is called, "Inhibition by phospholipids of haemolytic action of asbestos." by M C Jaurand, L Magne, J Bignon - Br J Ind Med 1979;36:113-116. Here is an excerpt: "Abstract - Haemolysis by asbestos fibres results from an increase in membrane permeability and not from rupture of red blood cells (RBC). The effect of chrysotile asbestos on RBC is at least partly, if not completely, attributable to lipid extraction and adsorption on to the fibres. This was suggested by the hyperbolic relationship between the haemolytic activity of chrysotile and the relative concentration of both chrysotile and RBC. Moreover, it was shown that pre-incubation of chrysotile with lipids, either as RBC membranes or with pure lipids in the form of liposomes, prevents haemolysis."
Another interesting study is called, "Lung function and exercise performance in smoking and nonsmoking asbestos-exposed workers." By Sue DY, Oren A, Hansen JE, Wasserman K. - Am Rev Respir Dis. 1985 Sep;132(3):612-8. Here is an excerpt: "Abstract - Evaluation of impairment caused by exposure to an occupational toxin can be complicated by additional exposure to other injurious agents. Because cigarette smoking is common and cigarettes are implicated in obstructive lung disease and cardiovascular diseases, we assessed the contribution of smoking to functional abnormalities in a group of asbestos-exposed shipyard workers. Seventy-three workers who never smoked were paired with 73 current smokers by age and asbestos exposure. Pulmonary function and performance during cycle incremental exercise were compared between the 2 groups. Nonsmokers had significantly higher VC, FEV1, FEV1/VC, and diffusing capacity for carbon monoxide than did smokers. Only 3 of the 73 nonsmokers but 23 of the 73 smokers had a FEV1/VC below the 95% confidence limit of predicted value. The FEF25-75%, on the other hand, failed to identify additional subjects with obstruction not found by the FEV1/VC. During exercise, despite no difference in maximal heart rate, the maximal O2 uptake (VO2max) and oxygen-pulse were lower among smokers. In addition, smokers more frequently had abnormal AaPO2 at maximal exercise. Of 33 smokers who had a VO2max less than 80% of predicted, 16 were judged to have cardiac disease, whereas only 2 appeared to be limited by obstruction. Only 15 of the 73 nonsmokers had a VO2max less than 80%. We conclude that cigarette smoking was the major contributing factor to the obstructive lung disease observed in asbestos workers, and it also had a strong influence on the occurrence, nature, and magnitude of exercise limitation. The history of cigarette smoking has an important effect on the assessment of impairment from asbestos."
We all owe a debt of gratitude to these fine researchers for their important work. If you found any of these excerpts helpful, please read the studies in their entirety.
Per Capita Asbestos Consumption Rate and Mesothelioma Incidence
By: Montwrobleski77
Uptake of Long Asbestos Fibers by the Metaplastic Squamous Mucosa Asbestos Fibers Extracted From Lung and Counted Ceasured and Identified by Morphologic Examination Mesothelioma Arising in the Pleura in the Case of Peritoneal Mesothelioma T-suppressor Cells Significantly Elevated among Asbestos Workers Chrysotile Properties and the Mesothelioma Plague Attributable Risk and Exposure to Asbestos Inflammatory Disorders and the Increased Occurrence of Mesothelioma Fiber Analysis and the Asbestos Exposure Menace Marginal Increases in Mean Tail Moments and Mesothelioma Cells Evaluating Benign and Malignant Lung and Pleural Masses in Asbestosis and Mesothelioma Top Five Age Spot Removal Treatments Genital Herpes Treatments That Effectively Eliminate Outbreaks Forever Treatment of Genital Herpes To Be Liberated From Any More Nasty Outbreaks