subject: Kamagra 100mg Tablets: Usage, Mechanism of Action and Safety Information [print this page]
Introduction
The Kamagra 100mg tablets are related to sildenafil, which belongs to the phosphodiesterase type-5 (PDE-5) inhibitors category of drugs. Sildenafil is used mainly for treating erectile dysfunction (ED), which implies inability to have or maintain an adequate erection needed for sexual intercourse. ED may happen due to various reasons such as cardiovascular disorders, diabetes, hypertension, medications, psychological disorders like stress and anxiety, smoking, alcohol intake, or some other health issues. In case if there are repeated erection problems, it is necessary to determine their causes as well.
What is Kamagra 100mg?
Kamagra 100mg is the name of a product related to sildenafil 100mg. Sildenafil cannot stimulate libido and does not belong to aphrodisiacs. The drug works only when it is sexually stimulated as it helps with the natural process of erection. 100 mg is one of the strengths of sildenafil, but it does not mean that 100 mg is a right dosage for each person. Prescribing information gives an opportunity to adjust the dosage depending on efficiency and tolerance of the drug, but the maximum frequency of administration should be once daily.
Working Mechanism of Sildenafil
Erection happens as a result of the relaxation of smooth muscles as well as an increase in the flow of blood into the penile tissues. As a result of sexual stimulation, there will be signalling of nitric oxide, resulting in the production of cyclic GMP (cGMP). PDE-5 enzyme normally acts to degrade cGMP. Sildenafil acts by blocking the PDE-5 enzyme, making cGMP activity continue and therefore contributing to the relaxation of the smooth muscles as well as an increase in penile blood flow. As a result, sildenafil cannot automatically cause an erection and therefore cannot be used to treat low sexual desires. Sexual stimulation is needed.
Uses of Kamagra 100mg
The major use of sildenafil in medicine is to treat erectile dysfunction. In the case of a suitable patient, sildenafil can help to:
- Produce erection on sexual stimulation - Maintain erection on sexual activity - Enhance blood flow response in erection - Addressing issues related to erectile dysfunction
There is individual variation in treatment effectiveness. Smoking, alcohol, lack of exercises, stress and obesity may also lead to erectile difficulties.
Dosage and Administration
Sildenafil tablets come in 25 mg, 50 mg, and 100 mg strengths. In relation to the cited brand of sildenafil, 50 mg is the standard starting dose, while 100 mg may be prescribed as a higher dose and 25 mg as a lower dose according to effectiveness and tolerability. The maximal recommended dosage frequency is once per day. In general, sildenafil is administered prior to sex, and sexual stimulation is necessary for the desired effect to be obtained. A large meal may slow down the absorption and the effect of sildenafil.
Important Drug Interactions
The most important safety consideration is that it is not safe to take sildenafil along with nitrate-based medications used for chest pain, including glyceryl trinitrate (GTN). The combination of these drugs may result in severe blood pressure lowering. FDA Access Data Sildenafil is also known to interact with alpha blockers, some blood pressure medicines, antibiotics, antifungals and some other medicines.
Final Information The term Kamagra 100mg Tablets is in relation to the drug sildenafil 100mg. The medicine helps to treat erectile dysfunction. This occurs since it inhibits PDE-5 and the cGMP pathway, thus allowing more blood into the penis during sexual stimulation. It cannot increase sexual desire nor create an erection without stimulation. Since sildenafil interacts with some other drugs and it is not for everybody, the correct dose will depend on personal health condition and ongoing treatment. More importantly, sildenafil should not be taken with any nitrate drugs due to dangers of hypotension.
